Dynamic changes of throat swabs RNA and serum antibodies for SARS-CoV-2 and their diagnostic performances in patients with COVID-19

Xueping Qiu, Yang Xiang, Jianbin Sun, Xinrui Wang, Guoqiang Chen, Xianqun Xu, Shengjun Liao, Na Yang, Siwei Li, Gang Yang, Yueting Tang, Junli Fan, Wen Xie, Hanning Hu, Yirong Li & Fang Zheng
Dynamic changes of RNA and antibodies in SARS-CoV-2 infected patients remain largely unknown, and influence factors for antibody production have not been fully clarified. In this study, consecutive throat swabs specimens (n = 1875) from 187 patients were collected to analyse the dynamic changes of RNA. Moreover, 162 serial serum samples from 31 patients were tested for seroconversion of IgM and IgG. Meanwhile, IgM and IgG were also detected in 409 COVID-19 patients and 389...
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