Individualized prognostic signature for pancreatic carcinoma validated by integrating immune-related gene pairs (IRGPs)

Yecheng Li, Pingan Yao, Kui Zhao, Zhenyu Ye, Haobo Zhang, Jianping Cao, Shuyu Zhang & Chungen Xing
Increasingly attention is being given to immune molecules in pancreatic cancer. The purpose of this study was to understand the potential clinical application of immune-regulated genes (IRGs) in the stratification of prognosis and to facilitate the development of personalized prognostic information for pancreatic cancer patients. We systematically used public data to comprehensively analyze immune-regulated gene pair (IRGP) expression profiles and clinical data. In our study, IRGP signature was identified to predict the overall survival (OS)...
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