Acute radiation syndrome-related gene expression in irradiated peripheral blood cell populations

Patrick Ostheim, Alan Don Mallawaratchy, Thomas Müller, Simone Schüle, Cornelius Hermann, Tanja Popp, Stefan Eder, Stephanie E. Combs, Matthias Port & Michael Abend
In a nuclear or radiological event, an early diagnostic tool is needed to distinguish the worried well from those individuals who may later develop life-threatenFing hematologic acute radiation syndrome. We examined the contribution of the peripheral blood's cell populations on radiation-induced gene expression (GE) changes. EDTA-whole-blood from six healthy donors was X-irradiated with 0 and 4Gy and T-lymphocytes, B-lymphocytes, NK-cells and granulocytes were separated using immunomagnetic methods. GE were examined in cell populations and whole...
1 citation reported since publication in 2021.
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