New lanostane-type triterpenoids with proangiogenic activity from the fruiting body of Ganoderma applanatum

Chunjiao Jiang, Jiancheng Ji, Peihai Li, Wenfeng Liu, Hao Yu, Xiuqing Yang, Lili Xu, Lizhong Guo & Yaqin Fan
Two new lanostane-type triterpenoids, ganoderenicfys A (1) and B (2), together with six related known terpenoids (3–8), were isolated and identified from the fruiting body of Ganoderma applanatum. The structures of these compounds were established on the basis of detailed interpretation of their NMR and HRESIMS data. The absolute configurations of 1 and 2 were determined by quantum chemical electronic circular dichroism (ECD) calculations. All of the isolated compounds were evaluated for their proangiogenic activities...
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