Infiltrating T-cell abundance combined with EMT-related gene expression as a prognostic factor of colon cancer

Xiaowei Huang, Chan Chen, Yajing Xu, Lanxiao Shen, Yi Chen & Huafang Su
EMT-related gene expression reportedly exhibits correlation with the anti-tumor immunity of T cells. In the present study, we explored the factors that might affect the efficacy of immunotherapy in colon cancer with treatment. In this regard, RNA-seq and clinical data of 469 colon cancer samples derived from the Cancer Genome Atlas (TCGA) database were used to calculate infiltrating T-cell abundance (ITA), to illustrate a pathway enrichment analysis, and to construct Cox proportional hazards (CPH) regression...
1 citation reported since publication in 2021.
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