Dynamic changes of plasma extracellular vesicle long RNAs during perioperative period of colorectal cancer

Qing Hua, Wenhao Xu, Xuefang Shen, Xi Tian, Hailiang Zhang, Yan Li & Pingbo Xu
Extracellular vesicles (EVs) long RNAs (exLRs) have been shown to be indicators for the diagnosis and prognosis of colorectal cancer (CRC); however, the dynamic changes of exLRs during perioperative period and their cellular sources in CRC remains largely unknown. In this study, exLR sequencing (exLR-seq) was performed on plasma samples from three CRC patients at four time points (before surgery [T0], after extubation [T1], 1 day after surgery [T2], and 3 days after surgery [T3])....
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