Identification of prognostic and bone metastatic alternative splicing signatures in bladder cancerRunzhi Huang, Zixuan Zheng, Shuyuan Xian, Jiayao Zhang, Jingyi Jia, Dianwen Song, Penghui Yan, Huabin Yin, Peng Hu, Xiaolong Zhu, Zongqiang Huang, Tong Meng & Jie Zhang
Bladder cancer (BLCA), originating from the epithelium of the urinary bladder, was the second most common malignancy in the urinary system with a high metastasis rate and poor post-metastasis prognosis. Alternative splicing events (ASEs) were regarded as important markers of tumor progression and prognosis, however, their roles in bladder cancer bone metastasis have not been recognized. In this study, we constructed a predictive model based on ASEs and explored the molecular mechanism of ASEs in...
1 citation reported since publication in 2021.
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