A new cycloheptane derivative from the fungus Penicillium crustosum JT-8

Jun-Tao Hu, Jia-Peng Wang, Yan Shu, Xue-Yun Cai, Cheng-Tong Sun, Hao Ding, Le Cai & Zhong-Tao Ding
A new highly oxygenated cycloheptane derivative crustane (1), along with fourteen known compounds (2–15) were isolated from Penicillium crustosum JT-8. The structure of compound 1 was determined by extensive spectroscopic data, DP4+ probability analyses and dimolybdenum CD method. Compound 1 exhibited moderate antibacterial activity against Staphylococcus aureus with MIC of 4.0 μg/mL.
1 citation reported since publication in 2021.
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