Evidence for the butyrate metabolism as key pathway improving ulcerative colitis in both pediatric and adult patients

Zheng Zhou, Jiasheng Cao, Xiaoming Liu & Mingsong Li
Accumulating evidence has shown many similarities and differences of gene profiles and pathways between pediatric and adult ulcerative colitis (UC) patients. In this study, we aimed to investigate the shared genes and pathways in intestinal tissues of pediatric and adult UC. Differentially expressed genes (DEGs) between pediatric and adult UC were identified via bioinformatic analysis of Gene Expression Omnibus datasets GSE87473 and GSE126124. Gene Ontology and pathway enrichment were used to analyze overlapped and distinguished...
1 citation reported since publication in 2021.
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