Comparative analysis of circular RNA enrichment methods

Huajuan Shi, Ying Zhou, Erteng Jia, Zhiyu Liu, Min Pan, Yunfei Bai, Xiangwei Zhao & Qinyu Ge
The circRNAs sequencing results vary due to the different enrichment methods and their performance is needed to systematic comparison. This study investigated the effects of different circRNA enrichment methods on sequencing results, including abundance and species of circRNAs, as well as the sensitivity and precision. This experiment was carried out by following four common circRNA enrichment methods: including ribosomal RNA depletion (rRNA–), polyadenylation and poly (A+) RNA depletion followed by RNase R treatment (polyA+RNase R),...
1 citation reported since publication in 2021.
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