An insight into SARS-CoV-2 membrane protein interaction with spike, envelope, and nucleocapsid proteins

Prateek Kumar, Amit Kumar, Neha Garg & Rajanish Giri
Intraviral protein–protein interactions are crucial for replication, pathogenicity, and viral assembly. Among these, virus assembly is a critical step as it regulates the arrangements of viral structural proteins and helps in the encapsulation of genomic material. SARS-CoV-2 structural proteins play an essential role in the self-rearrangement, RNA encapsulation, and mature virus particle formation. In SARS-CoV, the membrane protein interacts with the envelope and spike protein in Endoplasmic Reticulum Golgi Intermediate Complex (ERGIC) to form an...
1 citation reported since publication in 2021.
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