Integrated Analysis of DNA methylation and transcriptome profile to identify key features of age-related macular degeneration

Zhijie Wang, Yinhua Huang, Feixue Chu, Kai Liao, Zekai Cui, Jiansu Chen & Shibo Tang
Age-related macular degeneration (AMD) is a common vision-threatening disease. The current study sought to integrate DNA methylation with transcriptome profile to explore key features in AMD. Gene expression data were obtained from the Gene Expression Omnibus (GEO, accession ID: GSE135092) and DNA methylation data were obtained from the ArrayExpress repository (E-MTAB-7183). A total of 456 differentially expressed genes (DEGs) and 4827 intragenic differentially methylated CpGs (DMCs) were identified between AMD and controls. DEGs and DMCs...
1 citation reported since publication in 2021.
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.