Secreted phosphoprotein 1 as a potential prognostic and immunotherapy biomarker in multiple human cancers

Ping Zeng, Xujun Zhang, Tianxin Xiang, Zongxin Ling, Chenhong Lin & Hongyan Diao
Secreted phosphoprotein 1 (SPP1) is involved in immune regulation, cell survival, and tumor progression. Studies have demonstrated that SPP1 plays an important role in certain individual tumors. However, the expression profile and oncogenic features of SPP1 in diverse cancers are remaining unknown. Therefore, we performed a comprehensive analysis using The Cancer Genome Atlas (TCGA) database. Raw data of 33 cancer types were download from the University of California Santa Cruz (UCSC) Xena website. The expression...
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