Comprehensive analysis of peripheral blood non-coding RNAs identifies a diagnostic panel for fungal infection after transplantation
Anli Yang, Huadi Chen, Jianwei Lin, Ming Han, Xiaopeng Yuan, Tao Zhang, Qingwei Nian, Mengran Peng, Dian Li, Chenglin Wu & Xiaoshun He
The occurrence of fungal infection seriously affects the survival and life quality of transplanted patients. The accurate diagnosis is of particular importance in the early stage of infection. To develop a novel diagnostic method for this kind of patient, we established a post-transplant immunosuppressed mice model with fungus inoculation and collected their peripheral blood at specific time points after infection. After screening by microarray, differentially expressed miRNAs and lncRNAs were selected and homologously analyzed with...
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