A short report of novel RARG-HNRNPM fusion gene in resembling acute promyelocytic leukemia

Yang Song, Jiangxue Hou, Li Wan, Kaiqi Liu, Chunlin Zhou, Shuning Wei, Guangji Zhang, Dong Lin, Yan Li, Qiuyun Fang, Yuntao Liu, Benfa Gong, Xiaoyuan Gong, Ying Wang, Hui Wei, Jianxiang Wang & Yingchang Mi
Resembling acute promyelocytic leukemia (APL) is a unique subtype of APL who sharing clinical, morphological, and immunophenotypic features with typical APL, but lacking evidence of PML-RARA fusion gene and usually insensitive to arsenic trioxide (ATO) and all-trans retinoic acid (ATRA). For years, RARA, RARB and RARG rearrangement were found in resembling APL continually. The confirmed partner genes of RARG rearrangement included CPSF6, NUP98, NPM1, PML, and HNRNPC. These patients were a group of resembling APL...
1 citation reported since publication in 2022.
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