Protective effect and mechanism of low P50 haemoglobin oxygen carrier on isolated rat heart

Wentao Zhou, Shen Li, Shasha Hao, Honghui Zhang, Tao Li, Wanjing Li, Jiaxin Liu, Hong Wang & Chengmin Yang
The protection of the isolated heart is very important in heart transplantation surgery, meanwhile, the ischaemia/reperfusion (I/R) of the isolated heart is the main cause of its damage. A timely supply of oxygen can significantly improve the prevention of myocardial ischaemia, however, the cardioprotective solution does not have an oxygen supply function. Haemoglobin Based on Oxygen Carriers (HBOCs) is a kind of nano-oxygen drug, which can effectively and timely supply oxygen to hypoxic organs and...
1 citation reported since publication in 2022.
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