Molecular genetic and clinical characterization of acute myeloid leukemia with trisomy 8 as the sole chromosome abnormalityJie Liu, WenMin Han, Xiaohui Cai, Zheng Wang, LiuJun Cao, HaiYing Hua, ZhuXia Jia, HongYing Chao, XuZhang Lu & HongJie Shen
The aim of the study was to determine molecular genetic and clinical characterization of acute myeloid leukemia (AML) with trisomy 8 as the sole chromosome abnormality, a recurrent but rare chromosomal abnormality in AML. Interphase fluorescence in situ hybridization, reverse transcriptase-quantitative polymerase chain reaction for gene rearrangement and next-generation sequencing (NGS) were performed on sole trisomy 8 AML patients. A total of 35 AML patients with trisomy 8 as the sole chromosome abnormality were screened....
1 citation reported since publication in 2022.
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