Cardiac disorder-related adverse events for aryl hydrocarbon receptor agonists: a safety review

Xiaoxue Tian, Shufen Zheng, Jing Wang, Meiling Yu, Zhuoheng Lin, Min Qin, Yuanyuan Wu, Shiyu Chen & Shilong Zhong
Although cardiac disorder-related adverse events (AEs) have been reported in patients treated with aryl hydrocarbon receptor (AHR) agonists, their safety profiles remain unknown. Here, we identified significant cardiac disorders associated with AHR agonists and further evaluated their relevance. Database queries were performed using OpenVigil 2.1 and AEs voluntarily submitted to Food and Drug Administration Adverse Event Reporting System (FAERS) between 2004 and 2020 were included. This study based on the Medical Dictionary for Regulatory Activities...
1 citation reported since publication in 2022.
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