LncRNA-UCA1 regulates lung adenocarcinoma progression through competitive binding to miR-383

Li Tang, Sheng Wang, Yapeng Wang, Kang Li & Qiang Li
The present study aimed to assess the role of the long non-coding RNA-urothelial cancer associated 1 (lncRNA-UCA1)/microRNA (miR)-383/vascular endothelial growth factor A (VEGFA) axis in regulating lung adenocarcinoma physiology through in vivo and in vitro experiments. The expression profile of lncRNA-UCA1 was analyzed by genome-wide analysis from GSE146459. The cell counting Kit-8, colony formation, wound healing and transwell assays were performed to evaluate the effects of lncRNA-UCA1 in vitro. In addition, luciferase reporter assays were...
1 citation reported since publication in 2022.
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