Increased production of 8-oxo-7,8-dihydroguanine in human urine, a novel biomarker of osteoporosis

Qian Liu, Zhen Liu, Chen-Chen Wang, Xin Gao, Chuan-Bao Li, Meng Wang, Qiang Wang & Jian-Ping Cai
Osteoporosis is a worldwide disease that seriously affects the quality of life and survival rate of the elderly. The detection of bone biomarkers will provide supplementary information on bone mineral density, contributing to the accurate diagnosis of osteoporosis and better health care for prevention. This study aimed to investigate the efficacy of oxidative stress markers—8-oxo-7,8-dihydroguanine (8-oxoGsn) and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGsn) in the assessment of osteoporosis. We conducted a cross-sectional study among menopausal women with a mean...
1 citation reported since publication in 2022.
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