Anti-inflammatory and anti-allodynic activities in mice of the essential oil and desmethylisoencecalin from Zinnia grandiflora NuttallValeria Reyes-Pérez, Vinicio Granados-Soto, Edelmira Linares, Robert Bye, Rachel Mata & Myrna Deciga-Campos
Zinnia grandiflora (Asteraceae) is used to alleviate several painful disorders. The effects of an essential oil prepared by hydrodistillation from Z. grandiflora (EOZ) and its major compound on neuropathic pain, allodynia, and inflammation in mice were assessed. Headspace-solid phase microextraction analysis of an aqueous extract was also carried out. GC-MS analyses of all volatiles revealed that germacrene D (13.24%) and desmethylisoencecalin (DME) (13.24%) were the most abundant compounds. EOZ was effective in reducing inflammation and...
1 citation reported since publication in 2022.
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