Efficient synthesis of 3-hydroxy chromones via oxidative cyclization mediated by lipase

Jiapeng Li, Yue Yu, Yaning Xu, Fengxi Li, Yuqi Liu, Yifei Sun, Chunyu Wang, Peng Chen & Lei Wang
In this work, an efficient synthesis of 3-hydroxy chromones was accomplished through oxidative cyclization mediated by lipase. This enzymatic process has salient features of environmental friendliness, mild reaction condition, satisfactory yield, green reusable biocatalyst, and short reaction time. The proposed method expands the application of lipase in organic synthesis.
1 citation reported since publication in 2022.
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