Additional file 1 of VHHs as tools for therapeutic protein delivery to the central nervous system

Yessica Wouters, Tom Jaspers, Laura Rué, Lutgarde Serneels, Bart De Strooper & Maarten Dewilde
Additional file 1: Figure S1. Bivalent Nb62 fails to shuttle NT(8-13) into the brain. Mouse body temperature measurements are shown after 250 nmol/kg intravenous injections of the indicated VHH fused to NT(8-13). Bar graphs represent mean ± SEM (n = 3 per group). Statistical test: two-way ANOVA with repeated measures and Sidak’s multiple comparisons test. (significant time*treatment interaction effect ****p<0.0001).
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