Diagnostic signature and immune characteristic of aging-related genes from placentas in Preeclampsia

Xiufang Wang, Andong He, Ka Cheuk Yip, Xiaoting Liu & Ruiman Li
Preeclampsia (PE) is a serious pregnancy syndrome. Advanced maternal age (≥ 35 years old) is one of the major risk factors of PE and placental aging is considered to be related to this disease. However, the mechanisms underlying these phenomena remain obscured. Gene expression profiles of PE and non-PE placental samples were curated from the GSE75010 dataset. A diagnostic model was constructed and immune characteristics of PE subtypes were estimated. A total of 58 aging-related...
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