Additional file 2 of Using genetically encoded fluorescent biosensors to interrogate ovarian cancer metabolism

Shree Bose, Haipei Yao, Qiang Huang, Regina Whitaker, Christopher D. Kontos, Rebecca A. Previs & Xiling Shen
Additional file 2: Supplementary Figure 2. Biosensor responses to carboplatin treatment across heterogenous OC cell lines are negatively correlated with carboplatin resistance. Biosensor-expressing cell lines were treated with 100 μM carboplatin and iNap (A), Perceval (B), and Peredox (C) signal was measured at 24 and 48 hours. (D-F) Signal for each biosensor in (A-C) in treated cells was compared to that in control, untreated cells, normalized to 1 (n = 3 per condition). Normalized iNap...
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