Cloning of goat PGAM2 gene and its overexpression promotes the differentiation of intramuscular preadipocytes

Xiao Ma, Yuxue Wang, Xinyi Li, Jian Wang, Botao Wang, Yaqiu Lin & Yan Xiong
As a member of the PGAMs family, PGAM2 has been proved to catalyze the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. However, it is unclear whether PGAM2 has a role in regulating differentiation in goat intramuscular preadipocytes. Here, this study was carried to clone the open reading frame (ORF) of goat PGAM2, elucidate its molecular and expressional characteristics, and evaluate the involvement in adipogenesis of intramuscular preadipocytes. According to our...
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