Clinical outcomes and lung mechanics characteristics between COVID-19 and non-COVID-19-associated acute respiratory distress syndrome: a propensity score analysis of two major randomized trials
Bruno Martins Tomazini, Eduardo Leite Vieira Costa, Bruno Adler Maccagnan Pinheiro Besen, Fernando Godinho Zampieri, Carlos Roberto Ribeiro de Carvalho, Eliana Bernardete Caser, Vicente Cés de Souza-Dantas, Emerson Boschi, Renata Rego Lins Fumis, Meton Soares de Alencar Filho, Israel Silva Maia, Wilson de Oliveira Filho, Viviane Cordeiro Veiga, Alvaro Avezum, Renato Delascio Lopes, Flávia Ribeiro Machado, Otávio Berwanger, Regis Goulart Rosa, Alexandre Biasi Cavalcanti & Luciano César Pontes de Azevedo
ABSTRACT Objective: To compare the lung mechanics and outcomes between COVID-19-associated acute respiratory distress syndrome and non-COVID-19-associated acute respiratory distress syndrome. Methods: We combined data from two randomized trials in acute respiratory distress syndrome, one including only COVID-19 patients and the other including only patients without COVID-19, to determine whether COVID-19-associated acute respiratory distress syndrome is associated with higher 28-day mortality than non-COVID-19 acute respiratory distress syndrome and to examine the differences in lung mechanics...
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