Additional file 3: Fig. S2 SphK1 inhibitor PF543 suppressed adipocyte-induced metastasis of EOC cells. A Serum-starved SKOV3 and HEY cells were treated with increasing doses of PF543 as indicated for 2 h. Expression level of SphK1 was determined by Western blot and normalized to GAPDH. Densitometric analysis of SphK1 was shown on the right. Data are mean ± SD (n = 3). ns, no significance versus control; two-tailed Student’s t test. B Serum-starved SKOV3 and...