Airborne particulate matter impairs corneal epithelial cells migration via disturbing FAK/RhoA signaling pathway and cytoskeleton organization

Yu-Hong Cui, , , Xi-Ling Song, Qing-Yang Feng, Guang Yang, Zhi-Jie Li & Hong-Wei Pan
Background: Cornea is the outmost structure of the eye and exposed directly to the air pollution. However, little is known about the effect of PM2.5 on corneal epithelium, which is critical for maintenance of cornea homeostasis and visual function. Objective: We investigated the influence of PM2.5 exposure on corneal epithelial migration and the possible mechanisms involved in the process. Methods: We observed wound healing in mouse model of cornea abrasion, evaluated the migration and mobility...
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