Impact on acute myeloid leukemia relapse in granulocyte colony-stimulating factor application: a meta-analysis

Xiaoqin Feng, He Lan, Yongsheng Ruan & Chunfu Li
Objectives: This meta-analysis evaluated the impact of granulocyte colony-stimulating factor (G-CSF) added to chemotherapy on treatment outcomes including survival and disease recurrence in patients with acute myeloid leukemia (AML). Methods: Medline, Cochrane, EMBASE, and Google Scholar databases were searched until 19 September 2016 using search terms. Studies that investigated patients with AML who underwent stem-cell transplantation were included. Results: The overall analysis revealed a significant improvement in overall survival (OS) (P = .019) and disease-free survival (DFS)...
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