Synthesis and antioxidant activity of some new thioglycoluril derivatives

Imene Boudebouz, Salah Arrous, Evgenii Plotnikov, Olesya Voronova & Abdigali Bakibaev
A series of S-alkylated products was prepared by alkylation of thioglycoluril with various alkylation agents, i.e. ethyl bromide, ethylene dibromide and chloroacetic acid. The synthesis performed in DMF at 60°C using sodium hydroxide as a base to give the corresponding products with significant advantages such as high conversions, short reaction time, mild reaction conditions, and low cost, simple workup with moderate to excellent yields. The structures of the synthesized compounds have been deduced from their...
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