Identification of placental nutrient transporters associated with intrauterine growth restriction and pre-eclampsia

Xiao Huang, Pascale Anderle, Lu Hostettler, Marc Baumann, Daniel Surbek, Edgar Ontsouka & Christiane Albrecht
Abstract Background Gestational disorders such as intrauterine growth restriction (IUGR) and pre-eclampsia (PE) are main causes of poor perinatal outcomes worldwide. Both diseases are related with impaired materno-fetal nutrient transfer, but the crucial transport mechanisms underlying IUGR and PE are not fully elucidated. In this study, we aimed to identify membrane transporters highly associated with transplacental nutrient deficiencies in IUGR/PE. Results In silico analyses on the identification of differentially expressed nutrient transporters were conducted using...
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