Bone markers and cardiovascular risk in type 2 diabetes patients

Sabine Zwakenberg, Yvonne Schouw, Casper Schalkwijk, Annemieke Spijkerman & Joline Beulens
Abstract Background Vascular calcifications are associated with a three- to fourfold increased risk of cardiovascular disease (CVD) and are highly prevalent in type 2 diabetes patients. Emerging evidence indicates that vascular calcification is a process of active bone formation regulated by stimulators and inhibitors of calcification. Therefore, this study aimed to evaluate whether six bone markers are associated with CVD risk in patients with type 2 diabetes. Methods We used data of a case-cohort study,...
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