A multi-trait Bayesian method for mapping QTL and genomic prediction

Kathryn Kemper, Philip Bowman, Benjamin Hayes, Peter Visscher & Michael Goddard
Abstract Background Genomic prediction and quantitative trait loci (QTL) mapping typically analyze one trait at a time but this may ignore the possibility that one polymorphism affects multiple traits. The aim of this study was to develop a multivariate Bayesian approach that could be used for simultaneously elucidating genetic architecture, QTL mapping, and genomic prediction. Our approach uses information from multiple traits to divide markers into ‘unassociated’ (no association with any trait) and ‘associated’ (associated...
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