Saline versus 5% dextrose in water as a drug diluent for critically ill patients: a retrospective cohort study

Yukari Aoyagi, Takuo Yoshida, , Masanori Takinami & Shoichi Uezono
Abstract Background The choice of intravenous infusion products for critically ill patients has been studied extensively because it can affect prognosis. However, there has been little research on drug diluents in this context. The purpose of this study is to evaluate the impact of diluent choice (saline or 5% dextrose in water [D5W]) on electrolyte abnormalities, blood glucose control, incidence of acute kidney injury (AKI), and mortality. Methods This before-after, two-group comparative, retrospective study enrolled...
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