No change in the consumption of thyroid hormones after starting low dose naltrexone (LDN): a quasi-experimental before-after study

Guttorm Raknes & Lars Småbrekke
Abstract Background Low dose naltrexone (LDN) is reported to have beneficial effects in several autoimmune diseases. The purpose of this study was to examine whether starting LDN was followed by changes in the dispensing of thyroid hormones to patients with hypothyroidism. Methods We performed a quasi-experimental before-after study based on the Norwegian Prescription Database. Study participants were identified by using reimbursement codes for hypothyroidism. Cumulative dispensed Defined Daily Doses and the number of users of...
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