Identification of NEO1 as a prognostic biomarker and its effects on the progression of colorectal cancer

Meng Zhang, Zhou Zhou, , , Hai-Ou Li, Pei-Shan Qiu, , , Hai-Zhou Wang, Lan Liu, Jing Liu & Qiu Zhao
Abstract Background Due to the high morbidity and poor clinical outcomes, early predictive and prognostic biomarker identification is desiderated in colorectal cancer (CRC). As a homologue of the Deleted in Colorectal Cancer (DCC) gene, the role of Neogenin-1 (NEO1) in CRC remained unveiled. This study was designed to probe into the effects and potential function of NEO1 in CRC. Methods Online databases, Gene Set Enrichment Analysis (GSEA), quantitative real-time PCR and western blotting were used...
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