Overall survival in patients with re-excision of positive microscopic margins of limb and trunk wall soft tissue sarcoma operated outside of a reference center: a nationwide cohort analysis

Francois Gouin, Eberhard Stoeckle, Charles Honoré, Mickael Ropars, Mehrdad Jafari, Jean Camille Mattei, Alexandre Rochwerger, Sébastien Carrere, Denis Waast, Gwenaël Ferron, Jean-Christophe Machiavello, Philippe Anract, Frédéric Marchal, François Sirveaux, Oren Marco, Jérôme Guiramand, Brice Paquette, Antonio Di Marco, Sylvain Causeret, Jean-Marc Guilloit, Pauline Soibinet, Dimitri Tzanis, Pierre Gimbergues, Fabrice Fiorenza, Franck Dujardin … & Jean-Yves Blay
Abstract Background This French nationwide NETSARC exhaustive prospective cohort aims to explore the impact of systematic re-excision (RE) as adjuvant care on overall survival (OS), local recurrence free survival (LRFS), and local and distant control (RFS) in patients with soft tissue sarcoma (STS) with positive microscopic margins (R1) after initial resection performed outside of a reference center. Methods Eligible patients had experienced STS surgery outside a reference center from 2010 to 2017, and had R1...
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