Biosynthesized silver nanoparticles and miR34a mimics mediated activation of death receptor in MCF-7 human breast cancer cell lines

Muhammad Javed Iqbal, Umer Rashid, Zeeshan Javed, Zara Hamid, Komal Imran, Ayesha Kabeer, Shahid Raza, Zainab M. Almarhoon, Željko Reiner, Iulia-Cristina Bagiu, Radu Vasile Bagiu, Ioan Sarac, Javad Sharifi-Rad, Alibek Ydyrys, Sevgi Durna Daştan, Monica Butnariu & William C. Cho
Abstract Nano-biotechnology-based clinical applications to cure health-related issues have gained huge attention among the scientific community and hold great promise to limit cancer metastasis. In this study, green-derived silver nanoparticles were synthesized by using leaf extract of Litchi chinensis. Characterization of biosynthesized silver nanoparticles was performed by using UV–Vis spectroscopy, FTIR, XRD, EDS, and SEM analysis. The clinical application of green-drive nanoparticles was investigated by using MCF-7 cancer cell lines. MCF-7 breast cancer cell lines...
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