Sustained seropositivity up to 20.5 months after COVID-19

Carlota Dobaño, Anna Ramírez-Morros, Selena Alonso, Rocío Rubio, Gemma Ruiz-Olalla, Josep Vidal-Alaball, Dídac Macià, Queralt Miró Catalina, Marta Vidal, Aina Fuster Casanovas, Esther Prados de la Torre, Diana Barrios, Alfons Jiménez, Jasmina Zanoncello, Natalia Rodrigo Melero, Carlo Carolis, Luis Izquierdo, Ruth Aguilar, Gemma Moncunill & Anna Ruiz-Comellas
Abstract This study evaluated the persistence of IgM, IgA, and IgG to SARS-CoV-2 spike and nucleocapsid antigens up to 616 days since the onset of symptoms in a longitudinal cohort of 247 primary health care workers from Barcelona, Spain, followed up since the start of the pandemic. The study also assesses factors affecting antibody levels, including comorbidities and the responses to variants of concern as well as the frequency of reinfections. Despite a gradual and...
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