Screening for novel risk factors related to high myopia using machine learning

Ruiheng Zhang, Li Dong, Qiong Yang, Wenda Zhou, Haotian Wu, Yifan Li, Heyan Li & Wenbin Wei
Abstract Background High myopia-related complications have become a major cause of irreversible vision loss. Evaluating the association between potential factors and high myopia can provide insights into pathophysiologic mechanisms and further intervention targets for myopia progression. Method Participants aged 12–25 years from National Health and Nutrition Examination Survey 2001–2006 were selected for the analysis. Myopia was defined as spherical equivalent (sum of spherical error and half of the cylindrical error) of any eyes ≤-0.5 diopters....
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