Association between childhood trauma and medication adherence among patients with major depressive disorder: the moderating role of resilience

Hongqiong Wang, Yuhua Liao, Lan Guo, Huimin Zhang, Yingli Zhang, Wenjian Lai, Kayla M. Teopiz, Weidong Song, Dongjian Zhu, Lingjiang Li, Ciyong Lu, Beifang Fan & Roger S. McIntyre
Abstract Background Suboptimal medication adherence is a major reason for failure in the management of major depressive disorder (MDD), childhood trauma might be an essential risk factor of suboptimal medication adherence. This study aimed to comprehensively explore the associations between different types of childhood trauma and medication adherence among patients with MDD, and to test whether resilience has moderating effects on the foregoing associations. Methods Participants were from the Depression Cohort in China (ChiCTR registry...
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