NeRD: a multichannel neural network to predict cellular response of drugs by integrating multidimensional data

Xiaoxiao Cheng, Chong Dai, Yuqi Wen, Xiaoqi Wang, Xiaochen Bo, Song He & Shaoliang Peng
Abstract Background Considering the heterogeneity of tumors, it is a key issue in precision medicine to predict the drug response of each individual. The accumulation of various types of drug informatics and multi-omics data facilitates the development of efficient models for drug response prediction. However, the selection of high-quality data sources and the design of suitable methods remain a challenge. Methods In this paper, we design NeRD, a multidimensional data integration model based on the...
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