Identification of castration-dependent and -independent driver genes and pathways in castration-resistant prostate cancer (CRPC)

Yan Li, Hui Shi, Zhenjun Zhao & Minghui Xu
Abstract Background Prostate cancer (PCa) is one of the most diagnosed cancers in the world. PCa inevitably progresses to castration-resistant prostate cancer (CRPC) after androgen deprivation therapy treatment, and castration-resistant state means a shorter survival time than other causes. Here we aimed to define castration-dependent and -independent diver genes and molecular pathways in CRPC which are responsible for such lethal metastatic events. Methods By employing digital gene expression (DGE) profiling, the alterations of the epididymal...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.