Marijuana use and DNA methylation-based biological age in young adults

Drew R. Nannini, Yinan Zheng, Brian T. Joyce, Tao Gao, Lei Liu, David R. Jacobs, Pamela Schreiner, Chunyu Liu, Steve Horvath, Ake T. Lu, Kristine Yaffe, Stephen Sidney, Philip Greenland, Donald M. Lloyd-Jones & Lifang Hou
Abstract Background Marijuana is the third most commonly used drug in the USA and efforts to legalize it for medical and recreational use are growing. Despite the increase in use, marijuana’s effect on aging remains understudied and understanding the effects of marijuana on molecular aging may provide novel insights into the role of marijuana in the aging process. We therefore sought to investigate the association between cumulative and recent use of marijuana with epigenetic age...
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