C9orf16 represents the aberrant genetic programs and drives the progression of PDAC

Xiaojun Chen, Hong Zhang & Bo Xiao
Abstract Background Pancreatic ductal adenocarcinoma (PDAC), constituting 90% of pancreatic cancers, is the fourth leading cause of cancer-related deaths in the world. Lack of early detection of PDAC contributes to its poor prognosis as patients are often diagnosed at an advanced stage of disease. This is mostly due to the lack of promising diagnostic and therapeutic targets and corresponding drugs. Methods and results Here, by bioinformatic analysis of single cell RNA-sequencing data on normal pancreas...
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