Evidence for pharmacological interventions to reduce cardiovascular risk for patients with chronic kidney disease: a study protocol of an evidence map

Julia M. T. Colombijn, Demy L. Idema, Kim van der Braak, Rene Spijker, Sabine C. A. Meijvis, Michiel L. Bots, Lotty Hooft, Marianne C. Verhaar & Robin W. M. Vernooij
Abstract Background Patients with chronic kidney disease (CKD) require a personalised strategy for cardiovascular risk management (CVRM) to reduce their high risk of cardiovascular morbidity and mortality. Despite their high risk, patients with CKD appear to be underrepresented in randomised controlled trials (RCTs) for pharmacological CVRM interventions to reduce cardiovascular risk (pharmacological CVRM interventions). As a result, it remains unclear whether the efficacy of these interventions found in patients without CKD is similarly applicable to...
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