Imaging features associated with H3 K27-altered and H3 G34-mutant gliomas: a narrative systematic review

Arian Lasocki, Gehad Abdalla, Geoffrey Chow & Stefanie C. Thust
Abstract Background Advances in molecular diagnostics accomplished the discovery of two malignant glioma entities harboring alterations in the H3 histone: diffuse midline glioma, H3 K27-altered and diffuse hemispheric glioma, H3 G34-mutant. Radiogenomics research, which aims to correlate tumor imaging features with genotypes, has not comprehensively examined histone-altered gliomas (HAG). The aim of this research was to synthesize the current published data on imaging features associated with HAG. Methods A systematic search was performed in March...
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