Prevalence of familial autoimmune diseases in juvenile idiopathic arthritis: results from the international Pharmachild registry

Joeri W. van Straalen, Sytze de Roock, Gabriella Giancane, Ekaterina Alexeeva, Elena Koskova, Pablo Mesa-del-Castillo Bermejo, Francesco Zulian, Adele Civino, Davide Montin, Nico M. Wulffraat, Nicolino Ruperto & Joost F. Swart
Abstract Background Little is known about the disposition to autoimmune diseases (ADs) among children diagnosed with JIA. In this study, we provide a comprehensive overview of the prevalence of and factors associated with ADs in parents of children with juvenile idiopathic arthritis (JIA). Methods Prevalence rates of ADs and 95% Poisson confidence intervals were calculated for parents of JIA patients from the international Pharmachild registry and compared with general population prevalence rates as reported in...
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