Quantitative proteomics identified circulating biomarkers in lung adenocarcinoma diagnosis

Hongyu Chen, Xiaoqin Lai, Yihan Zhu, Hong Huang, Lingyan Zeng & Li Zhang
Abstract Background Lung cancer (LC) is a common malignant tumor with a high incidence and poor prognosis. Early LC could be cured, but the 5-year-survival rate for patients advanced is extremely low. Early screening of tumor biomarkers through plasma could allow more LC to be detected at an early stage, leading to a earlier treatment and a better prognosis. Methods This study was based on total proteomic analysis and parallel reaction monitoring validation of peripheral...
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